EQVALAN DUO
Contra-indications,
warnings, etc
Safety studies were not conducted in foals younger than 2 months
of age, nor in stallions, therefore EQVALAN DUO cannot be
recommended for use in these categories of animals.
The
use of EQVALAN DUO may be dangerous to aquatic life. Horses
should not have direct access to surface waters and ditches
during treatment.
EQVALAN DUO has been formulated for use in horses only. Cats,
dogs, especially Collies, Old English Sheepdogs and related
breeds or crosses, and also turtles and tortoises may be
adversely affected by the concentration of ivermectin in this
product if they are allowed to ingest spilled paste or have
access to used syringes.
Parasite resistance to any particular class of anthelmintic may
develop following frequent, repeated use of an anthelmintic of
that class.
Some
horses with heavy infections of
Onchocerca
spp. microfilariae have experienced oedema and pruritus
following treatment, assumed to be the result of the death of
large numbers of microfilariae. These signs resolve within a few
days but symptomatic treatment may be advisable. In cases of
heavy infestations with tapeworms, signs of mild, transient
colic and diarrhoea may be observed. There have been rare
reports of swelling and irritation of the mouth, lip and tongue,
and of salivation following administration of EQVALAN DUO. These
reactions have been transitory in nature, appearing within 1
hour and abating within 24-48 hours following administration.
No
undesirable effects related to treatment were observed in 2
month old horses treated with EQVALAN DUO at up to three times
the recommended dose and in adult horses treated at ten times
the recommended dose. Transient decreased food consumption,
increased body temperature and impairment of vision were noticed
in horses treated twice with an ivermectin oral paste at ten
times the recommended dose (i.e., 2 mg/kg b.w.). All changes
disappeared within five days. No antidote has been identified;
however, symptomatic therapy may be beneficial.
Use during
pregnancy and lactation
Ivermectin-Praziquantel combination can be used after the first
three months of gestation and during lactation. In the absence
of clinical data in early pregnancy EQVALAN DUO can only be used
in the first three months of gestation according to a risk
benefit analysis by the veterinarian.
Withdrawal
periods
Meat: 30 days. Do not use in mares producing milk for human
consumption.
Container
disposal
EXTREMELY DANGEROUS FOR FISH AND AQUATIC LIFE. Do not
contaminate surface waters or ditches with product or used
syringes. Dispose of any unused product and empty syringes in
accordance with guidance from your local waste regulation
authority.
For animal treatment only.
This product may cause skin and eye irritation. Therefore, the
user should avoid contact of the product with the skin and eyes.
In case of contact, rinse immediately with plenty of water.
In the case of accidental ingestion or eye irritation after
contact seek medical advice immediately and show the package
insert or the label to the physician.
Uses
For the treatment of mixed cestode (tapeworm) and nematode
(roundworm) or arthropod (bot) infestations in horses.
The following parasites of horses are sensitive to the
antiparasitic effects of EQVALAN DUO:
Tapeworms:
Anoplocephala perfoliata
Large strongyles:
Strongylus vulgaris (adults and arterial larval stages)
Strongylus edentatus (adults and tissue larval stages)
Strongylus equinus (adults)
Triodontophorus spp (adults)
Triodontophorus brevicauda
Triodontophorus serratus
Craterostomum acuticaudatum (adults)
Adult and immature (fourth-stage larvae)
small strongyles or cyathostomes, including
benzimidazole-resistant strains:
Coronocyclus spp
Coronocyclus coronatus
Coronocyclus labiatus
Coronocyclus labratus
Cyathostomum spp
Cyathostomum catinatum
Cyathostomum pateratum
Cylicocyclus spp
Cylicocyclus ashworthi
Cylicocyclus elongatus
Cylicocyclus insigne
Cylicocyclus leptostomum
Cylicocyclus nassatus
Cylicodontophorus spp
Cylicodontophorus bicornatus
Cylicostephanus spp
Cylicostephanus calicatus
Cylicostephanus goldi
Cylicostephanus longibursatus
Cylicostephanus minutus
Parapoteriostomum spp
Parapoteriostomum mettami
Petrovinema spp
Petrovinema poculatum
Poteriostomum spp
Adult hairworms:
Trichostrongylus axei
Adult and immature pinworms:
Oxyuris equi
Adult, third- and fourth-stage larvae of roundworms (ascarids):
Parascaris equorum
Microfilariae
of neck threadworms:
Onchocerca spp
Adult intestinal threadworms:
Strongyloides westeri
Adult large-mouth stomach worms:
Habronema muscae
Oral and gastric stages of bots:
Gasterophilus spp
Adult and immature lungworms:
Dictyocaulus arnfieldi
18/02/2010
